CD2 anticorps
Aperçu rapide pour CD2 anticorps (ABIN3024314)
Antigène
Voir toutes CD2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Purification
- Protein G affinity chromatography
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Immunogène
- Recombinant human protein was used as the immunogen for the CD2 antibody.
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Isotype
- IgG1 kappa
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Indications d'application
- Optimal dilution of the CD2 antibody should be determined by the researcher.\. Flow Cytometry: 0.5-1 μg/million cells in 0.1ml,Immunofluorescence: 0.5-1 μg/mL
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Restrictions
- For Research Use only
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Concentration
- 1 mg/mL
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Buffer
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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Agent conservateur
- Azide free
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store the CD2 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
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- CD2
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Autre désignation
- CD2
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Sujet
- CD2 interacts through its amino-terminal domain with the extracellular domain of CD58 (also designated CD2 ligand) to mediate cell adhesion. CD2/CD58 binding can enhance antigen-specific T cell activation. CD2 is a transmembrane glycoprotein that is expressed on peripheral blood T lymphocytes, NK cells and thymocytes. CD58 is a heavily glycosylated protein with a broad tissue distribution in hematopoietic and other cells, including endothelium. Interaction between CD2 and its counter receptor LFA3 (CD58) on opposing cells optimizes immune system recognition, thereby facilitating communication between helper T lymphocytes and antigen-presenting cells, as well as between cytolytic effectors and target cells.
Antigène
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